If you experience any of the following, you may be
experiencing Weight Loss Resistance:


Does this sound like you?

  • You have excess weight around the midsection
  • You have a history of going on diets over and over again
  • You experience fatigue shortly after meals or around 3pm
  • You crave salty foods, junk food, baked goods and sweets
  • You’ve tried keto, paleo,  vegan, carnivore and other “diets” but still struggle with with your weight.
  • You’ve tried cardio, weights, CrossFit, and just about every other exercise program with limited results.

Do you ever think, “I have a very healthy lifestyle and my weight or numbers just don’t reflect it?”

There’s a reason…. Most people will not like this at all. Please relax and remember, it’s just information.

Metabolic Memory. That’s what the process is called and why even with strict changes and plenty of time sticking to them, things still aren’t right.

Certain cells and workings within the cells of our most important metabolic tissues have been damaged. The energy production and energy storing cells of our muscles and fat simply are not working properly. Energy production is not only low in these cases, but very inefficient causing free radical damage inside the cells and to our mRNA that expresses and copies our genes.

I think this potentially irreversible damage occurs from being chronically in the fed state coupled by high levels of sugar and processed food in our diets as children.

80 lbs weight loss

Kids eat so often their insulin exposure is constant throughout the day keeping them in the fed metabolic state. They also eat WAY too much added sugar in all forms making up 17% of their daily food. Processed foods like bread, pancakes, and mass-produced snacks make up 45-50% of their diets. The American Academy of Pediatrics recommend a limit 25 grams per day of added sugar, a number that is about 5 times too high.

The fed state reduces the natural repair state and the consequent detoxification, recycling, and upkeep of our energy machinery. This especially impacts the Smooth Endoplasmic Reticulum where a lot of this would take place and where glucose transport molecules are made (GLUT-4).

The constant burning of sugar all day long wears our energy factories down and makes them less efficient. The lack of repair being expressed decreases and recycling keeping old and inefficient cells on the job long after their retirement age which prohibits new healthy factories from being made and introduced.

In Insulin Resistance there is up to an 86% reduction in those glucose transport molecules that bring glucose from the blood and into storage as glycogen and body fat. This breaks down the natural metabolism flow and we see all the complications of obesity, diabetes, heart disease, and systemic inflammation develop.

Therefore, attempts to lower blood sugar by medications, natural supplements, and keto/paleo/carnivore/vegan diets do not stop the disease complications from occurring. You may have better blood sugar numbers, but you also have 3 times the rate of heart attacks (ADA), 10 times more women dying from a heart attack than breast cancer (AHA), retinopathy, limb amputations, blindness, impotence, and a 9–12-year reduction in life expectancy.

This is a lot to take in.

priority weight loss

The good news is you can change that physiology, it doesn’t have to be permanent. It takes very specific work done in cycles in relatively close proximity over time to change. Then once changed it will take a lifetime of upkeep. But hey, we know exactly what happens if we do nothing…… Not acceptable.

There is hope and I would like to help you learn what has been shown to take people off the road to chronic diseases and life ending complications.

Just know, that 80% of this damage is done before any symptoms show up. Before blood sugar is out of range, before blood pressure rises or we gain the extra weight. If these things have already happened to you then you are probably somewhere on this road we don’t want to go down.

We can do better!
Dr. Don

The Insulin Friendly Living model for improving insulin resistance and advanced metabolic health conditions comes from his years of work with patients, clients and participants in custom one on one programs to very large groups of thousands of people in the population health space.

His health, weightloss and wellness programs and strategies have now reached hundreds of thousands of people across the U.S. and internationally. He now combines this experience with years of clinical work to build one of the most comprehensive integrative lifestyle programs available today.

Dr. Clum’s has a truly unique approach in utilizing well documented lifestyle modifications of Variable Output Exercise, Stress Resilience practices, Sleep recovery, and his unique application of nutritional timing emphasizing when to eat as much as what to eat. These lifestyle modifications coupled by his Functional Fasting methods following a Rotational Fasting Calendar has caught the attention of industry leaders in both the holistic and conventional medical model. People have used his programs to improve significant metabolic health issues from weight loss resistance to problems on the insulin resistance spectrum including metabolic syndrome, pre and type 2 diabetes, thyroid and adrenal conditions, as well as addiction and early depression in men.

Dr. Don Clum graduated from Life University in Marietta, GA in 1997 with a degree in Human Nutrition. He then moved to Life Chiropractic College West in California where he graduated with his Doctorate of Chiropractic in 2000. After graduation, Dr. Clum moved to San Jose, Costa Rica where he was invited to work with the Costa Rican Olympic Committee and Athletes.

After eight years in Costa Rica, Dr. Clum traveled to Castilla La Mancha, Spain, where he practiced and did consulting for two years.

He returned to the U.S.A. in 2010 when he and his wife started a fully integrated wellness center bringing holistic services of chiropractic, massage, metabolic nutrition, metabolic workouts in their onsite gym, wellness psychology, and medical services collaboration. Dr. Clum also collaborated in transitioning a traditional pain management medical practice into a wellness center with holistic services and served as the director of the onsite lab.

Dr. Clum’s success in creating integrated programs for insulin resistance specifically focusing on diabetes, diabetes prevention, metabolic syndrome, weight loss resistance, obesity, and cardiometabolic issues led him to join a national corporate wellness and population health company, ADURO Inc., in 2014 to date serving 140 employers and over 1,200,000 employees. While at ADURO Dr. Clum designed and delivered the first alternative diabetes prevention program that rivals and beats the national statistics of the National Diabetes Prevention Program from the N.I.H., and C.D.C.


  1. Ihnat, M., Thorpe, J., & Ceriello, A. (2007). Hypothesis: the ‘metabolic memory’, the new challenge of diabetes. Diabetic Medicine, 24(6)
  2. Reddy, M., Zhang, E., & Natarajan, R. (2015). Epigenetic mechanisms in diabetic complications and metabolic memory. Diabetologia, 58(3), 443-455.
  3.  Misra, A., & Bloomgarden, Z. (2018). Metabolic memory: Evolving concepts. Journal of Diabetes, 10(3), 186-187.
  4.  Garvey WT, Maianu L, Huecksteadt TP, Birnbaum MJ, Molina JM, Ciaraldi TP. Pretranslational suppression of a glucose transporter protein causes insulin resistance in adipocytes from patients with non-insulin-dependent diabetes mellitus and obesity. J Clin Invest. 1991 Mar;87(3):1072-81. doi: 10.1172/JCI115068. PMID: 1999488; PMCID: PMC329903.